Signal & Noise

Signal & Noise

For four years, the 'experts' told you to shut up and 'trust the science'. What they failed to mention is that a lot of the science is wrong.

'Fringe Epidemiologist' and NIH Director,Jay Bhattacharya, isn't shy about sharing how he plans to get science back on track.

Tiffany Ryder's avatar
Tiffany Ryder
Feb 11, 2026
∙ Paid
Pic I snapped from my seat.

NIH spends $50 billion a year funding research - most of which doesn’t hold up under scientific scrutiny. Pharmaceutical companies publicly admit they can only replicate a small fraction of landmark studies they use to develop drugs. And your doctor makes clinical decisions about your treatment based on study outcomes that often amount to no more than fairy tales. (See HRT.)

But until recently, nobody with power seemed to give a sh*t about the reproducibility crisis - at least until NIH Director Jay Bhattacharya decided to make it his problem.

And I know you might be thinking:

The knowledge that studies can’t be replicated must be new or someone would have done something. It isn’t.

Maybe the problem’s being exaggerated or made up. It’s not.

Unfortunately there are receipts. Timestamped ones. And they prove my claim is far from conspiratorial.

Over a decade ago Amgen tried to reproduce the outcomes of 53 high-impact cancer studies. They confirmed only six. Tha…

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