Signal & Noise

Signal & Noise

Why Won't America's Top Vaccine Experts Defend Their Own Science?

Paul Offit & Peter Hotez were offered the opportunity of a lifetime- to refute skeptics of vaccine science in front of the committee making recommendations (& the public). So why did they decline?

Tiffany Ryder's avatar
Tiffany Ryder
Dec 08, 2025
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Aaron Siri was invited to address ACIP last week. And according to ACIP secretary Mina Zadeh, so were vaccine industry experts Paul Offit and Peter Hotez.

Siri showed up. Offit and Hotez did not.

That’s the summary. But it’s not the whole story.

ACIP - the Advisory Committee on Immunization Practices - is the body that sets vaccine recommendations for every American child. Last week, they reconsidered the hepatitis B birth dose - objectively a minor policy change,- but one that many people, including Offit and Hotez - were extremely upset about.

Siri, an attorney who has spent years representing vaccine-injured families, delivered a 90-minute presentation questioning the evidentiary basis for the childhood vaccine schedule.

The cornerstone of his arguments were:

  1. Most vaccines on the schedule have not been tested for safety against an inert placebo making safety claims unreliable.

  2. Trial sizes for vaccines have been under-powered or inadequate (not big enough) to determine safety with confi…

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